UMR-S 1193 HEPAREG

Physiopathogenesis and treatment of liver diseases

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From the director

The joint research unit UMR-S 1193/HEPAREG Inserm/Paris-Saclay University was founded on January 1, 2015 through the merge of UMR-S 785 with the training and research unit EA4530.
On January 1, 2020, the unit expanded by merging with UMR-S 1174/ICPH.
The research unit 1193/HEPAREG is made up of five teams, bringing together scientists and clinicians with strong recognition and expertise in research fields ranging from liver transplantation to the development of therapeutic strategies against fulminant hepatitis and primary liver cancers .

Pr Didier Samuel

Research teams

TEAM 1
Therapeutic Innovations in Liver Disease and Liver Transplantation
Translational Research
Pr Didier SAMUEL
Dr Ama GASSAMA-DIAGNE
Pr Eric VIBERT
Dr Audrey COILLY
TEAM 2
Liver organoid bioconstruction
Modelling and signatures of liver diseases
Dr François LE NAOUR
Dr Anne DUBART-KUPPERSCHMITT




TEAM 3
Microbiota, inflammation and liver cancer
Pr Jamilla FAIVRE





TEAM 4
Biliary homeostasis and liver repair
Dr Thierry TORDJMANN





TEAM 5
Cellular and molecular mechanisms of stress adaptation
Pr Christian POÜS


Where to find us?

The Hepato-Biliary Center at Paul Brousse Hospital, Villejuif

The HBC hosts our research teams 1, 2 and 3.
The goal of the CHB is to develop comprehensive care of patients with liver and/or biliary diseases (hepatic diseases, portal hypertension, complex biliary lesions) by creating a real "Liver Institute" by gathering at the same place a team of surgeons, physicians, endoscopists, radiologists, anesthesiologists, resuscitators, researchers as well as techniques and means. This global care is done throughout the life of a patient according to the evolution of his disease and the different therapeutic or monitoring stages.

Henri Moissan Building – Biology-Pharmacy-Chemistry Pole, Saclay

The Henri Moissan building will host our research teams 4 and 5 from October 2022.
In the meantime, Team 4 is located at: Department of Sciences of Paris-Saclay University in Orsay, building 440-443, and Team 5 at: Department of Pharmacy of Paris-Saclay University in Chatenay-Malabry, tower D4, 1st floor.

Authorities / Affiliations